Candida parapsilosis responsive to caspofungin in a preterm infant

Infectious Diseases and Tropical Medicine 2015; 1 (3): e138

  Topic: Fungal Infection     Category:

Betta P.
Department of Maternal-Child, University of Catania, Neonatal Intensive Care Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy Close
, Saporito A.
Department of Maternal-Child, University of Catania, Neonatal Intensive Care Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy Close
, Trovato L.
Department of Biomedical and Biotechnological Sciences, University of Catania, Laboratory Analysis Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy
trova.laura@libero.it Close
, Oliveri S.
Department of Biomedical and Biotechnological Sciences, University of Catania, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy Close

Abstract

The incidence of candidemia in the neonatal intensive care unit (NICU) is steadily increasing, with an estimated incidence of 1.6 to 9% in very-low-birth-weight infants and 15% in extremely-low-birth-weight infants. Here we report the case of a refractory candidemia by Candida parapsilosis successfully treated with caspofungin in a premature infant. The use of lysis centrifugation blood culture permitted to isolate Candida parapsilosis and the infant responded well to antifungal treatment, with a prompt improvement of his clinical condition. Caspofungin seems to be a valid option for infants with invasive candidiasis refractory to conventional antifungal therapy.

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To cite this article

Betta P.
Department of Maternal-Child, University of Catania, Neonatal Intensive Care Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy Close
, Saporito A.
Department of Maternal-Child, University of Catania, Neonatal Intensive Care Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy Close
, Trovato L.
Department of Biomedical and Biotechnological Sciences, University of Catania, Laboratory Analysis Unit, A.O.U. “Policlinico-Vittorio Emanuele”, Catania, Italy
trova.laura@libero.it Close
, Oliveri S.
Department of Biomedical and Biotechnological Sciences, University of Catania, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy Close
Candida parapsilosis responsive to caspofungin in a preterm infant

Infectious Diseases and Tropical Medicine 2015; 1 (3): e138

Publication History

Published online: 01 Oct 2015