Neisseria meningitidis is a global cause of morbidity and mortality, both in children and young adults, through sepsis and/or purulent meningitis. Humans are the only known reservoir. In order to decrease the burden of meningococcal related permanent sequelae and fatalities, a high level of clinical suspicion and prompt effective antibiotic treatment are mandatory. Here we present a case of a 36-year-old man admitted to our hospital for fever and a single petechial lesion due to Neisseria meningitidis.