The outbreak of 2019-novel Coronavirus disease (COVID-19) can be traced back to December 2019, when a cluster of patients with pneumonia of unknown etiology was found in Wuhan City, China. Diagnosis of COVID-19 may be challenging in children, since its clinical presentation overlaps with other viral upper and lower airways infections (i.e. influenza virus and respiratory syncytial virus), and they can occur as co-infection in/up to 40% of symptomatic cases. It has been observed a broad spectrum of clinical presentation for COVID-19, ranging from asymptomatic or mild to severe cases with severe acute respiratory distress, which may require intensive care. The aim of this paper is to provide an update on current data about COVID-19 in children.